Bioprinting 101: Part 7 – Applications

We have discussed a lot about materials within bioprinting as well as different printers that are used to work on bioprinting technology. We have not had an in-depth focus on current applications within bioprinting. We have briefly discussed a couple in articles, but will take a look at some interesting applications of bioprinting within the clinical setting.

Bioprinting must be very precise in terms of material preservation and creation. One must take into account that the body is very particular. It operates at specific temperatures and pH levels in order to sustain life. Typically bioprinted objects refer to structures we want to use for the body. For this to work they have to be of the following nature: completely mimicking an object within the body, or being able to morph into an object within the body due to biological reactivity. Both approaches are difficult in their own ways.

3D Printed Spinal Cord

It is difficult to mimic certain vascular structures within an organ or tissue. This requires extreme precision. Usually, a technology that helps with this is related to MRI, CT Scans, and other typical imaging software because it allows for ready made 3D objects to be created. However, the problem then lies within how accurate the imaging is on the outside of an object, as well as the inside morphology. Something like a liver, for example, has not just a hollow exterior, but also a complex inner structure.

It is difficult to only have a bioprinted object that relies on bioactivity to take the form of a structure previously in the body. The reason for this lies in needing to be extremely precise with material generation. The precision of a biomaterial and its production forces us to have precise analytical chemistry skills as well as biochemistry knowledge to understand the impact of trying to make a uniform biomaterial with enough bioactivity to evolve into a living organ. The natural fear one would have is the possible rapid development of said object within the body. Hence the fear of cancerous growth is not unfounded. Also, there is a concern that the body may just reject the foreign item that is trying to be used within the body.

  Sub $300 exiii handiii 3D Printed Open Source Bionic Hand is Controlled by a Smartphone

CT Scan of the Abdomen

Let us take a look into orthopedics. If we are to apply the method of mimicking bone structure within the body here are the problems likely to be faced:

  1. We are likely to have trouble matching the specific structure that is needed for an individual bone wise.
  2. We are fearful of the nanostructure of the material and how it may corrode or degenerate over time.
  3. We are also worried about biochemical reactivity based on the biomaterials we use to print out a piece of orthopedic material and how this may lead to toxicity problems for a patient in the future.

3D Printed Heart

If we are to apply the method of having a material that can morph into a biomaterial such as a bone within the body, here are the ramifications:

  1. We are worried about over reactivity and cancerous growth.
  2. We are also worried about under reactivity and needing to have continual surgeries.
  3. We are also worried about initial rejection of the material by the body.

The way to approach this problem within bioprinting and clinical methods, typically has been focused on combining these two processes of biomimicry and adaptive reactivity. However there are some interesting technologies that are leading to more options within the bioprinting industry as a whole. I will report on these in a couple of articles soon.

If you're looking to request photorealistic CGI in the USA, our service offers an easy and efficient way to get stunning, lifelike renderings for your architectural and real estate projects. Through our platform, you can quickly request high-quality CGI images that accurately capture the essence of your designs. Whether it's for a residential or commercial property, our experts specialize in creating realistic 3D renderings that highlight every detail, bringing your vision to life with exceptional clarity and precision.

  SOLS Launches the #SOLSonBowery Pop-up Shop to Creatively Market Their 3D Printed Insoles

Through our website, requesting photorealistic CGI becomes a seamless experience. With our help, you can get highly detailed 3D visualizations that look just like photographs, providing a realistic representation of your project before it's even built. Our team ensures that every element, from textures to lighting, is meticulously rendered, giving you an impressive, lifelike result that will leave a lasting impact on your clients and stakeholders.

Leave a Reply